Rheumatology Secrets, 5th Edition — Practical Q&A Review for Clinicians
For over 30 years the Secrets Series® has been a trusted resource for quick reference and exam review. Rheumatology Secrets 5th edition, edited by Jason Kolfenbach and Sterling G. West, offers updated coverage of immunology, pathophysiology, and clinical management in a question-and-answer format designed to make learning efficient and engaging.
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100+board-style questions
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5thedition
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2editors
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2026publication
Inside this resource
Immunology and pathophysiology foundations
The opening sections build a solid grounding in basic immunology as it applies to rheumatic disease — from autoimmune mechanisms to the molecular pathways driving inflammation. This foundation supports everything that follows in the clinical chapters.
Disease-specific chapters with the Secrets format
Each rheumatic condition is covered through the signature Q&A format: focused questions followed by concise, expert answers. Lists, tables, and pearls appear throughout, making it easy to review conditions from rheumatoid arthritis and lupus to vasculitis and crystal arthropathies.
Clinical management and new therapies
Practical chapters address treatment decisions, drug information, and monitoring strategies — keeping pace with the rapidly evolving therapeutic landscape in rheumatology, including biologics, biosimilars, and targeted synthetic DMARDs.
Board review and exam preparation
More than 100 board-style questions available online provide effective practice, while the Top 100 Secrets and Key Points boxes throughout the text give a fast overview of the most essential material for success on exams and in clinical practice.
Who this serves
- Rheumatology fellows — preparing for the ABIM Rheumatology Certification Exam and needing a concise, structured review resource
- Practicing rheumatologists — looking for a quick reference to stay current on disease management and emerging therapies
- Internal medicine physicians — who encounter rheumatic conditions in their practice and want a focused guide to common and uncommon disorders
- Medical students and residents — building foundational knowledge in rheumatology through an accessible Q&A format
Before you buy
What’s new in the 5th edition?
Fully revised and updated throughout, with a new chapter on IgG4-related disease, updated treatment options and drug information, and expanded coverage of new techniques and technologies in rheumatology.
Does the eBook include online question access?
Yes — more than 100 board-style questions are available online with the eBook, providing additional practice beyond the Q&A format in the text itself.
The chart
| Format | eBook (True PDF) |
|---|---|
| Edition | 5th |
| Editors | Jason Kolfenbach, Sterling G. West |
| Publisher | Elsevier |
| ISBN | 978-0443127946 |
| Department | Rheumatology |
| Delivery | Instant download after checkout · lifetime re-access |
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Emily W. –
Good companion to larger textbooks. The pathophysiology sections are concise but thorough enough to refresh foundational concepts before diving into clinical chapters.
drtomh –
This is my go-to quick reference in clinic. The tables on drug monitoring and treatment algorithms save me time looking things up during busy days.
J. Patel –
Solid resource for the price. The Top 100 Secrets boxes are genuinely useful for last-minute exam review. I just wish the online questions were more numerous.
M. Santos –
Bought this for my rheumatology rotation and it quickly became indispensable. The memory aids and pearls scattered throughout are genuinely helpful for retention.
Karen M. –
The Q&A format is perfect for between-patient review. The new IgG4 chapter fills a gap that other rheumatology texts ignore. Great for board prep.
A. Gupta –
Decent content but the PDF formatting could use work — some tables don’t render properly on smaller screens. The clinical information itself is solid.